MDS and PE

Thank you Dr. Ann George for yesterday's talk on anemia secondary to MDS.
Here is a good reference for MDS.

Today we went through a case of recurrent PE.

Here is a link to our last talk on PE where we reviewed wells criteria. 


This NEJM study compared Heparin and ALEPLASE (a TPA) vs heparin alone and showed that in SUBMASSIVE PE (and RV dysfunction) but NO hypotention (since that would be the definition of Massive PE) that there was less escalation in therapy with TPA... no change in death.... IE this is still an area of uncertainty.

Indications for thrombolysis is hypotension (sBP<90 mmHg)

Review of acute PE is HERE