- Churg-Strauss vasculitis has recently been renamed as 'eosinophilic granulomatosis with polyangiitis' or EGPA. It is a vasculitis involving small and medium-sized blood vessels
- The American College of Rheumatology diagnostic criteria for EGPA includes 4 or more of:
1) Asthma - often precedes the vasculitis, and may be difficult to control
2) Eosinophilia >10%
3) Neuropathy - most common is mononeuritis multiplex
4) Migratory pulmonary opacities on CXR
5) Paranasal sinus disease - allergic rhinitis, sinusitis, nasal polyposis possible
6) Biopsy confirming eosinophilic accumulation
- Other organ involvement (ie. GN) is also possible
- Yesterday we talked about the DDx of dyspnea in a patient with EGPA vasculitis. This includes an asthma exacerbation, pulmonary hemorrhage/vasculitis, cardiac involvement, or infection in a patient on immunosuppressants. Patients with EGPA may also be at an increased risk of DVT/PE
No comments:
Post a Comment