Monday 13 August 2012

IE

Hope everyone had a good weekend

Today we started off the week talking about a blue team patient who was admitted last week with a high suspicion of endocarditis. We discussed how although our patients are often IVDU, most commonly IE occurs in older patients who are not drug users.

We reviewed the DUKE's CRITERIA: since to make a diagnosis you need 2 major criteria, or 1 major and 2 minor, or 5 minor. 


Major Criteria:

1. Positive blood cultures for endocarditis.

  • high risk microorganisms on 2 blood cultures (separated by time) (Strep, Staph, Enterococcus, HACEK etc). THese should be persistent (i.e. over a 12 hour period) and positive for typical IE organisms
  • Single positive blood culture for Coxiella burnetii 
2. Evidence of endocardial involvment
  • Echocardiographic evidence
  • A NEW regurgitant murmer.
Minor Criteria:
  1. Fever >38 degrees C
  1. High risk- e.g. cardiac lesion or IV drug use.
  1. Vascular phenomena: arterial emboli, septic pulmonary infarcts, mycotic aneurysm, intracranial hemorrhage, conjunctival hemorrhages, Janeway lesions.
  1. Immunologic phenomena: glomerulonephritis, Osler's nodes, Roth spots, positive rheumatoid factor.
  1. Microbiologic evidence: positive blood culture not meeting major criterion 

Remember: Dukes is for LEFT sided lesions and right sides lesions do not have the same presentation in terms of vascular phenomena or easily heard murmur.



Here is a link the american heart association recommendations 

Happy monday.




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